Jobs - Join our Team

Scientist - Biomaterials and Product Assembly Development

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Position Overview: 

As a Scientist in the Biomaterials and Product Assembly Development (BMPAD) team, you will play a vital role in the development of our innovative therapies. Collaborating closely with cross-functional teams, you'll contribute to the development of key manufacturing processes for the assembly of our combination drug/device products, which consist of therapeutic cells/tissue, hydrogels, and biocompatible surfaces. Your achievements will be pivotal for enabling preclinical and clinical development of our therapies.

 

Key Responsibilities: 

 

• Develop manufacturing methods for the assembly of a combination drug/device product to enable clinical and commercial scale-up.

• Contribute to the development of analytical methods to assess key attributes of the combination drug/device product.

• Collaborate with cross-functional teams to facilitate technology transfers and implement phase-appropriate product assembly methods from research to clinical stages.

• Support Process Development and Preclinical Development with assembly of combination device and drug products.

• Design detailed experimental plans, including clear objectives, rationales, methodologies, data analysis strategies, and defined deliverables.

• Conduct hands-on experiments and ensure accurate, real-time data collection.

• Analyze complex analytical data, prepare comprehensive reports, and provide insights to support multidisciplinary teams.

• Author, review, and update Standard Operating Procedures (SOPs) to ensure consistency and compliance.

• Mentor junior team members and promote a culture of scientific excellence within the Product Development team.

• Collaborate effectively within cross-functional teams, encouraging open communication and fostering a positive and productive environment.

• Support the operation and maintenance of key equipment and instrumentation, ensuring optimal performance.

• Actively participate in workplace safety initiatives and adhere to policies, taking on relevant roles to ensure compliance.

• Drive continuous improvement by refining workflows and optimizing team processes.
   

Required Qualifications: 
 

• Ph.D. or M.Sc. in Materials Science, Biomedical Engineering, Chemical Engineering, or a related field.

• Extensive experience with hydrogel systems, ideally polyethylene glycol (PEG) hydrogels.

• Expertise in analytical methods for evaluating hydrogels (e.g., rheology, swelling properties, crosslinking density, mechanical testing, degradation studies).

• Hands-on experience with mammalian cell culture, including maintaining and expanding cells.

• Familiarity with basic cell assays (e.g., viability, proliferation, metabolic assays) to assess the interaction between cells and encapsulation materials.

• Experience with encapsulating living cells in hydrogels or similar biomaterials, with enthusiasm for contributing to the development and optimization of novel assembly processes.

• Track record of creative problem-solving in the context of process development and engineering challenges, including scale-up.

• Ability to plan, execute, and document experiments and process optimization studies.

• Experience working collaboratively in cross-disciplinary teams, including material scientists, biologists, and engineers.

• Strong data analysis skills to evaluate the performance and scalability of new manufacturing methods.

• Excellent verbal and written communication skills for presenting data and progress to internal teams and stakeholders.

• Proficiency in technical writing, including experiment outlines, drafting protocols, and reports.

Preferred Qualifications:
 

• Knowledge of manufacturing techniques for combination drug-device products.

• Familiarity with biocompatible materials and membrane engineering.

• Proven ability to develop novel devices and methods for product assembly and manufacturing.

• Hands-on experience with mammalian cell culture, including maintaining and expanding primary cells or stem cell-derived organoids[GU1] .

• Demonstrated ability to design and scale up manufacturing processes while maintaining critical quality attributes.

• Experience in phase-appropriate development, balancing innovation with the rigor needed for clinical and commercial scale-up.

• Strong understanding of quality-by-design principles and regulatory considerations for cell- and material-based therapeutics.

• Familiarity with tools for statistical analysis and design of experiments (DOE).

• Knowledge of regulatory requirements for cell-based therapies and combination products.

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Why Morphocell: 
 

• Join a dynamic team of professionals committed to pushing the boundaries of cell therapy. 

•  Contribute to groundbreaking advancements in the field of biotechnology. 

• Opportunity for personal and professional growth in a fast-paced and collaborative environment. 

• Competitive compensation package.

• Group medical and dental insurance.

• RRSP matching contribution.

• Commuting travel benefits.
   

If you're a driven scientist with a passion for analytical development in the realm of cell therapy, we invite you to apply for the Scientist role. Join us in our mission to redefine healthcare through innovative cell therapies. 
 

To apply, please submit your resume and cover letter to: career@morphocell.com .